NAP-2, CXCL7, human

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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NAP-2, CXCL7, human
CAT: RC312-18
DG: No
Storage: (-15 to -20)C

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NAP-2, CXCL7, human
CAT: RC312-18
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: NAP-2, CXCL7, human: Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and to chemoattract and activate neutrophils. Although CTAP-III, β-TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity., UnitProt ID: P02775

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