MIP-3, CCL23, human CAT.#: RC315-34

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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MIP-3, CCL23, human
CAT: RC315-34
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C

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MIP-3, CCL23, human
CAT: RC315-34
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2mm filtered concentrated (1.0mg/ml) solution in 20mM PB, pH 7.4, 150mM NaCl.

Product Description: MIP-3, CCL23, human: MIP-3/CCL23 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Alternative splicing of the MPIF1 gene results in two mRNAs that encode a short (CKβ8) and a long (CKβ81) isoform of the chemokine. CKβ8 cDNA encodes a 120 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide that is cleaved to generate a 99 aa residue mature CKβ8 (aa 22 120). Additional N terminal processing of the 99 aa residue variant can generate a 75 aa residue CKβ8 (aa 46 120) that is significantly more active than the 99 aa residue variant., UnitProt ID: P55773

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