MIP-1 beta, CCL4, rat

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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MIP-1 beta, CCL4, rat
CAT: RC355-15
Purity: > 95 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C

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MIP-1 beta, CCL4, rat
CAT: RC355-15
Purity: > 95 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2 µm filtered concentrated solution in 2 × PBS, pH 7.4, 3 % trehalose

Product Description: MIP-1 beta, CCL4, rat: Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. Recombinant CCL4 induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Furthermore, recombinant rat CCL4 contains 69 amino acids and it shares 80 % and 86 % a.a. sequence identity with human and murine CCL4. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells., UnitProt ID: P50230

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