IL-5, Interleukin-5, rat

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-5, Interleukin-5, rat
CAT: RC252-16
DG: No
Storage: (-15 to -20)C

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IL-5, Interleukin-5, rat
CAT: RC252-16
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: IL-5, Interleukin-5, rat: IL-5, also named B-cell differentiation factor I, eosinophil differentiation factor and TRF, is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin secretion. It is also a key mediator in eosinophil activation. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Rat IL-5 is a 132-amino acid (115 in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer., UnitProt ID: Q08125

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