IL-36 alpha (153 a.a.), human

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-36 alpha (153 a.a.), human
CAT: RC212-47B
DG: No
Storage: (-15 to -20)C

 

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IL-36 alpha (153 a.a.), human
CAT: RC212-47B
DG: No
Storage: (-15 to -20)C
Sterile: Yes
Stock: Inquire

Product Description: IL-36 alpha (153 a.a.), human: Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. Studies showed IL-36α is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. Notably, IL-36 alpha is the only novel IL-1 family member expressed on T-cells. Recombinant human interleukin-36 alpha (153 a.a.) contains 153 amino acids residues which is a single non-glycosylated polypeptide and it shares 57 – 68 % a.a. sequence identity with mouse, rabbit, equine and bovine IL-36α and 27 – 57 % a.a. sequence identity with other novel IL-1 family members., UnitProt ID: Q9UHA7

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