IL-2, Interleukin-2, porcine

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-2, Interleukin-2, porcine
CAT: RC282-13
Purity: > 96 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C

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IL-2, Interleukin-2, porcine
CAT: RC282-13
Purity: > 96 % by SDS-PAGE and HPLC analyses.
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2 mm filtered concentrated solution in 1 × PBS, pH 7.4

Product Description: IL-2, Interleukin-2, porcine: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55 kDa IL2Rα, 75 kDa IL2Rβ, 64 kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes. Recombinant porcine IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 72 % amino acid sequence identity with mouse, human and rat IL-2. It also shares 60 % and 67 % acid sequence identity with rhesus macaque and equus caballus IL-2, respectively., UnitProt ID: P26891

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