IL-13, Interleukin-13, murine (mouse)

Thương hiệu: Bio Basic-Canada   |   Tình trạng: Còn hàng
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IL-13, Interleukin-13, murine (mouse)
CAT: RC232-24
Purity: >97% by SDS-PAGE and HPLC analyses
Storage: (-15 to -20)C

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IL-13, Interleukin-13, murine (mouse)
CAT: RC232-24
Purity: >97% by SDS-PAGE and HPLC analyses
Storage: (-15 to -20)C
Sterile: Yes
Formulation: Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4

Product Description: IL-13, Interleukin-13, murine (mouse): IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive., UnitProt ID: P20109

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